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Saccharomyces cerevisiae (S288c)

RAD3

REM1, TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3, L000001557, YER171W

5' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress

GO Process (6)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

nucleotide-excision repair, DNA incision [IDA]

phosphorylation of RNA polymerase II C-terminal domain [IDA]

positive regulation of mitotic recombination [IMP]

regulation of mitotic recombination [IMP]

regulation of transposition, RNA-mediated [IMP]

transcription from RNA polymerase II promoter [IDA]

Gene Ontology Molecular Function

ATP-dependent 5'-3' DNA helicase activity [IDA]
core RNA polymerase binding transcription factor activity [IC]
damaged DNA binding [IDA]

Gene Ontology Cellular Component

core TFIIH complex [IDA]

holo TFIIH complex [IDA]

nucleotide-excision repair factor 3 complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

36924

559292

Interactors 200
Interactions 313
Network
PTM Sites 7