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Saccharomyces cerevisiae (S288c)

CLA4

ERC10, serine/threonine protein kinase CLA4, L000000564, L000002643, YNL298W

Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication

Kinome Project (Sc)

GO Process (8)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

negative regulation of gene expression [IGI, IMP]

positive regulation of protein import into nucleus [IMP]

protein phosphorylation [IDA]

regulation of exit from mitosis [IMP]

response to pheromone [IGI]

septin ring organization [IGI, IMP]

sterol import [IMP]

vacuole inheritance [IGI, IMP]

Gene Ontology Molecular Function

kinase activity [IDA]
protein kinase activity [IDA]
protein serine/threonine kinase activity [IDA]

Gene Ontology Cellular Component

cellular bud [IDA]

fungal-type vacuole [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

35540

559292

Interactors 754
Interactions 1,466
Network
PTM Sites 15