Saccharomyces cerevisiae (S288c)

MRPL3

mitochondrial 54S ribosomal protein YmL3, YmL3, L000002683, YMR024W
Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type
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  • Interactors 134
  • Interactions 162
  • Network
  • PTM Sites 1