Saccharomyces cerevisiae (S288c)

YPF1

YKL100C
Intramembrane aspartyl protease of the perinuclear ER membrane; acts in a branch of ER-associated degradation (ERAD) that degrades functional proteins rather than misfolded proteins; regulates abundance of high-affinity plasma membrane transporters during the starvation response; has a presenilin fold; member of the GxGD family of intramembrane proteases; closest human homolog is signal peptide peptidase (SPP)
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34033
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  • Interactors 71
  • Interactions 76
  • Network
  • PTM Sites 4