Saccharomyces cerevisiae (S288c)

HUL5

ubiquitin-ubiquitin ligase HUL5, YGL141W

Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD

UPS Project

GO Process (4)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

ER-associated ubiquitin-dependent protein catabolic process [IMP]

free ubiquitin chain polymerization [IMP]

protein polyubiquitination [IDA]

protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA]

Gene Ontology Molecular Function

ubiquitin-ubiquitin ligase activity [IDA]

Gene Ontology Cellular Component

cytoplasm [IDA]

nucleus [IDA]

proteasome complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33111

559292

Interactors 90
Interactions 97
Network
PTM Sites 10

Result Summary

HUL5

Gene Ontology Biological Process

Gene Ontology Molecular Function

ubiquitin-ubiquitin ligase activity [IDA]

Gene Ontology Cellular Component