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Saccharomyces cerevisiae (S288c)

ATG12

APG12, L000004702, YBR217W

Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p cojugate also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation

GO Process (6)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

C-terminal protein lipidation [IDA]

CVT pathway [IMP]

autophagic vacuole assembly [IMP]

late nucleophagy [IMP]

mitochondrion degradation [IMP]

piecemeal microautophagy of nucleus [IMP]

Gene Ontology Molecular Function

Atg8 ligase activity [IDA]
enzyme activator activity [IDA]
protein tag [IPI]

Gene Ontology Cellular Component

Atg12-Atg5-Atg16 complex [IDA]

pre-autophagosomal structure [IC]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32914

559292

Interactors 222
Interactions 285
Network