YDR159W / SAC3

Description: Nuclear pore-associated protein; required for biogenesis of the small ribosomal subunit; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay

Other Aliases: LEP1

External IDs: S000002566 (sgd),